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Glaucoma suspect

MedGen UID:
9027
Concept ID:
C0017614
Disease or Syndrome
Synonyms: Glaucoma, Suspect; Glaucomas, Suspect; Suspect Glaucoma; Suspect Glaucomas
SNOMED CT: Glaucoma suspect (833278008)

Definition

At least 1 of these in 1 eye: optic nerve or nerve fibre layer suggestive of glaucoma; abnormal visual field consistent with glaucoma; an elevated IOP > 22 mm Hg. [from SNOMEDCT_US]

Professional guidelines

PubMed

Quérat L, Chen E
Acta Ophthalmol 2023 Mar;101(2):e246-e251. Epub 2022 Sep 22 doi: 10.1111/aos.15256. PMID: 36147012
Susanna R Jr, Clement C, Goldberg I, Hatanaka M
Clin Exp Ophthalmol 2017 Aug;45(6):625-631. Epub 2017 Mar 9 doi: 10.1111/ceo.12925. PMID: 28164419
Chang RT, Singh K
Asia Pac J Ophthalmol (Phila) 2016 Jan-Feb;5(1):32-7. doi: 10.1097/APO.0000000000000173. PMID: 26886117

Recent clinical studies

Etiology

Somi MH, Nikniaz Z, Ostadrahimi A, Naghibi Irvani SS, Nourizadeh AM, Mirzaei M, Alipour F, Jafari F, Faramarzi E
Sci Rep 2023 May 17;13(1):7998. doi: 10.1038/s41598-023-30212-y. PMID: 37198199Free PMC Article
Hein JC, Tauber J, Shrivastava A
Curr Opin Ophthalmol 2023 Jul 1;34(4):290-295. Epub 2023 Mar 29 doi: 10.1097/ICU.0000000000000954. PMID: 36995100
Kletke SN, Mills MD, Tomlinson LA, Yu Y, Ying GS, Binenbaum G
J AAPOS 2022 Oct;26(5):236.e1-236.e6. Epub 2022 Sep 14 doi: 10.1016/j.jaapos.2022.05.010. PMID: 36113699
Kamalipour A, Moghimi S, Hou H, Penteado RC, Oh WH, Proudfoot JA, El-Nimri N, Ekici E, Rezapour J, Zangwill LM, Bowd C, Weinreb RN
Ophthalmology 2021 Oct;128(10):1426-1437. Epub 2021 Apr 2 doi: 10.1016/j.ophtha.2021.03.036. PMID: 33819524Free PMC Article
Chang RT, Singh K
Asia Pac J Ophthalmol (Phila) 2016 Jan-Feb;5(1):32-7. doi: 10.1097/APO.0000000000000173. PMID: 26886117

Diagnosis

Quintero M, Mihailovic A, Sikder S, Jun AS, Daoud Y, Ramulu PY
J Glaucoma 2023 Aug 1;32(8):631-639. Epub 2023 May 25 doi: 10.1097/IJG.0000000000002244. PMID: 37311015
Leshno A, Liebmann JM
Asia Pac J Ophthalmol (Phila) 2022 Nov 1;11(6):503-504. doi: 10.1097/APO.0000000000000564. PMID: 36278943
Kletke SN, Mills MD, Tomlinson LA, Yu Y, Ying GS, Binenbaum G
J AAPOS 2022 Oct;26(5):236.e1-236.e6. Epub 2022 Sep 14 doi: 10.1016/j.jaapos.2022.05.010. PMID: 36113699
Blumberg DM, De Moraes CG, Liebmann JM, Garg R, Chen C, Theventhiran A, Hood DC
Invest Ophthalmol Vis Sci 2016 Jul 1;57(9):OCT80-5. doi: 10.1167/iovs.15-18931. PMID: 27409509Free PMC Article
Chang RT, Singh K
Asia Pac J Ophthalmol (Phila) 2016 Jan-Feb;5(1):32-7. doi: 10.1097/APO.0000000000000173. PMID: 26886117

Therapy

Ha A, Sun S, Kim YK, Jeoung JW, Kim HC, Park KH
Br J Ophthalmol 2024 Jun 20;108(7):927-932. doi: 10.1136/bjo-2022-323167. PMID: 37918891
Mahmoudinezhad G, Nishida T, Weinreb RN, Baxter SL, Chang AC, Nikkhoy N, Walker E, Liebmann JM, Girkin CA, Moghimi S
BMJ Open 2023 Oct 4;13(10):e072163. doi: 10.1136/bmjopen-2023-072163. PMID: 37793935Free PMC Article
Somi MH, Nikniaz Z, Ostadrahimi A, Naghibi Irvani SS, Nourizadeh AM, Mirzaei M, Alipour F, Jafari F, Faramarzi E
Sci Rep 2023 May 17;13(1):7998. doi: 10.1038/s41598-023-30212-y. PMID: 37198199Free PMC Article
Freedman SF, Kraker RT, Repka MX, Wallace DK, de Alba Campomanes A, Yanovitch TL, Orge FH, Gearinger MD; Pediatric Eye Disease Investigator Group (PEDIG)
JAMA Ophthalmol 2020 Jan 1;138(1):71-75. doi: 10.1001/jamaophthalmol.2019.4571. PMID: 31750862Free PMC Article
Susanna R Jr, Clement C, Goldberg I, Hatanaka M
Clin Exp Ophthalmol 2017 Aug;45(6):625-631. Epub 2017 Mar 9 doi: 10.1111/ceo.12925. PMID: 28164419

Prognosis

Kletke SN, Mills MD, Tomlinson LA, Yu Y, Ying GS, Binenbaum G
J AAPOS 2022 Oct;26(5):236.e1-236.e6. Epub 2022 Sep 14 doi: 10.1016/j.jaapos.2022.05.010. PMID: 36113699
Quinn MP, Johnson D, Whitehead M, Gill SS, Campbell RJ
J Glaucoma 2021 Jun 1;30(6):e300-e304. doi: 10.1097/IJG.0000000000001792. PMID: 33449589
Berchuck S, Jammal A, Mukherjee S, Somers T, Medeiros FA
Br J Ophthalmol 2021 Sep;105(9):1244-1249. Epub 2020 Aug 29 doi: 10.1136/bjophthalmol-2020-316617. PMID: 32862132Free PMC Article
Potop V, Corbu C, Coviltir V, Schmitzer S, Constantin M, Burcel M, Ionescu C, Dăscălescu D
Rom J Ophthalmol 2019 Oct-Dec;63(4):321-326. PMID: 31915729Free PMC Article
Blumberg DM, De Moraes CG, Liebmann JM, Garg R, Chen C, Theventhiran A, Hood DC
Invest Ophthalmol Vis Sci 2016 Jul 1;57(9):OCT80-5. doi: 10.1167/iovs.15-18931. PMID: 27409509Free PMC Article

Clinical prediction guides

Ha A, Sun S, Kim YK, Jeoung JW, Kim HC, Park KH
Br J Ophthalmol 2024 Jun 20;108(7):927-932. doi: 10.1136/bjo-2022-323167. PMID: 37918891
Abbasi A, Antony BJ, Gowrisankaran S, Wollstein G, Schuman JS, Ishikawa H
Transl Vis Sci Technol 2023 Aug 1;12(8):6. doi: 10.1167/tvst.12.8.6. PMID: 37555737Free PMC Article
Kletke SN, Mills MD, Tomlinson LA, Yu Y, Ying GS, Binenbaum G
J AAPOS 2022 Oct;26(5):236.e1-236.e6. Epub 2022 Sep 14 doi: 10.1016/j.jaapos.2022.05.010. PMID: 36113699
Kamalipour A, Moghimi S, Hou H, Penteado RC, Oh WH, Proudfoot JA, El-Nimri N, Ekici E, Rezapour J, Zangwill LM, Bowd C, Weinreb RN
Ophthalmology 2021 Oct;128(10):1426-1437. Epub 2021 Apr 2 doi: 10.1016/j.ophtha.2021.03.036. PMID: 33819524Free PMC Article
Quinn MP, Johnson D, Whitehead M, Gill SS, Campbell RJ
J Glaucoma 2021 Jun 1;30(6):e300-e304. doi: 10.1097/IJG.0000000000001792. PMID: 33449589

Recent systematic reviews

Wu Z, Karunaratne S, Ang GS, Martin KR, Downie LE
Clin Exp Ophthalmol 2024 May-Jun;52(4):416-430. Epub 2023 Dec 13 doi: 10.1111/ceo.14339. PMID: 38093486

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